Saltar al contenido
Merck

RBM8A

RNA binding motif protein 8A

Sinónimos:
BOV-1A, BOV-1B, BOV-1C, C1DELq21.1, DEL1q21.1, MDS014, RBM8, RBM8B, TAR, Y14, ZNRP, ZRNP1
Especie:
ID UniProtKB:
ID del gen:
  • Human(9939) Summary: This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. [provided by RefSeq, Jul 2013]
  • Mouse(60365) RNA binding motif protein 8a
  • Rat(295284) RNA binding motif protein 8A
  • Zebrafish(503767) RNA binding motif protein 8A
  • domestic cat(101098563) RNA binding motif protein 8A
  • Horse(100034052) RNA binding motif protein 8A
  • dog(475827) RNA binding motif protein 8A
  • domestic guinea pig(100731698) RNA binding motif protein 8A
  • naked mole-rat(101702668) RNA binding motif protein 8A
  • cow(518045) RNA binding motif protein 8A
  • sheep(101117890) RNA binding motif protein 8A

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Y14 Antibody, clone 4C4, clone 4C4, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-Y14/RBM8A Antibody, clone 5K5E6, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Rbm8a,
Especie
mouse
MISSION® esiRNA, targeting human RBM8A,
Especie
human