PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Sinónimos:
COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2
Especie:
Human PTGS2 (5743), Mouse Ptgs2 (19225), Rat Ptgs2 (29527), cow PTGS2 (282023), sheep PTGS2 (443460), Goat PTGS2 (100860905), naked mole-rat Ptgs2 (101704771), Domestic Rabbit PTGS2 (100009248), domestic guinea pig Ptgs2 (100135607), chicken PTGS2 (396451) ...Más
ID UniProtKB:
ID del gen:
- Human(5743) Summary: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
- Mouse(19225) prostaglandin-endoperoxide synthase 2
- Rat(29527) prostaglandin-endoperoxide synthase 2
- cow(282023) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- sheep(443460) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- Goat(100860905) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- naked mole-rat(101704771) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- Domestic Rabbit(100009248) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- domestic guinea pig(100135607) prostaglandin-endoperoxide synthase 2
- chicken(396451) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- Horse(791253) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- domestic cat(100126581) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
- dog(442942) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-COX2/PTGS2 Antibody, clone 2V7G8, Rabbit Monoclonal, ,
Reactividad de especies
mouse
Aplicación
immunohistochemistry
western blot
western blot
Anti-Cyclooxygenase-2 Antibody, Chemicon®, from rabbit,
Reactividad de especies
bovine, human, mouse, sheep
Aplicación
ELISA
western blot
western blot
Anti-COX2, C-Terminal Rabbit pAb, liquid, Calbiochem®,
Reactividad de especies
bovine, human, mouse, rat, sheep
Aplicación
Small Molecule - Blocker
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Descripción
Especie
Small Molecule - Inhibitor
Referencia del producto
Descripción
Especie
Proteins
Referencia del producto
Descripción
Especie
Cyclooxygenase 2 human, ≥70% (SDS-PAGE), recombinant, expressed in insect cells, aqueous solution, ≥8000 units/mg protein,
Especie
human