PRKCG
protein kinase C, gamma
Sinónimos:
PKC-gamma, PKCC, PKCG, SCA14
Especie:
Human PRKCG (5582), Mouse Prkcg (18752), Rat Prkcg (24681), Zebrafish prkcg (100003514), dog PRKCG (484316), Horse PRKCG (100062549), domestic cat PRKCG (101082196), domestic guinea pig Prkcg (100733947), Domestic Rabbit PRKCG (100009102), naked mole-rat Prkcg (101698346) ...Más
ID UniProtKB:
ID del gen:
- Human(5582) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). [provided by RefSeq, Jul 2008]
- Mouse(18752) protein kinase C, gamma
- Rat(24681) protein kinase C, gamma
- Zebrafish(100003514) protein kinase C, gamma
- dog(484316) protein kinase C, gamma
- Horse(100062549) protein kinase C, gamma
- domestic cat(101082196) protein kinase C, gamma
- domestic guinea pig(100733947) protein kinase C, gamma
- Domestic Rabbit(100009102) protein kinase C, gamma
- naked mole-rat(101698346) protein kinase C, gamma
- cow(282002) protein kinase C, gamma
- sheep(101116423) protein kinase C, gamma
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Small Molecule - Agonist
Referencia del producto
Descripción
Especie
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PKCγ Antibody, clone 2B9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, rat
Aplicación
affinity binding assay
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-PKC gamma Antibody, clone 5F2X3, Rabbit Monoclonal, ,
Reactividad de especies
mouse, rat
Aplicación
western blot
Anti-p-PKCγ (Thr514) Antibody, clone 4F20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
inhibition assay
western blot
inhibition assay
western blot
Small Molecule - Inhibitor
Proteins
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Descripción
Especie
PKCγ, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
esiRNA
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Descripción
Especie