PRG2
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
Sinónimos:
BMPG, MBP, MBP1
Especie:
ID UniProtKB:
ID del gen:
- Human(5553) Summary: The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
- Mouse(19074) proteoglycan 2, bone marrow
- Rat(58826) proteoglycan 2, bone marrow
- Horse(100062803) proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Eosinophil Major Basic Protein Antibody, clone BMK13, clone BMK13, Chemicon®, from mouse,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PXDN/VPO1 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
bovine, human, mouse
Aplicación
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
esiRNA
Referencia del producto
Descripción
Especie