PRF1
perforin 1 (pore forming protein)
Sinónimos:
FLH2, HPLH2, P1, PFN1, PFP
Especie:
Human PRF1 (5551), Mouse Prf1 (18646), Rat Prf1 (50669), Thale Cress PRF1 (816495), Horse PRF1 (100072744), domestic cat PRF1 (100113473), dog PRF1 (489030), chicken PRF1 (427784), naked mole-rat Prf1 (101717851), domestic guinea pig Prf1 (100730283) ...Más
ID UniProtKB:
ID del gen:
- Human(5551) Summary: The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
- Mouse(18646) perforin 1 (pore forming protein)
- Rat(50669) perforin 1 (pore forming protein)
- Thale Cress(816495) profilin 1
- Horse(100072744) perforin 1 (pore forming protein)
- domestic cat(100113473) perforin 1 (pore forming protein)
- dog(489030) perforin 1 (pore forming protein)
- chicken(427784) perforin 1 (pore forming protein)
- naked mole-rat(101717851) perforin 1 (pore forming protein)
- domestic guinea pig(100730283) perforin 1 (pore forming protein)
- cow(369025) perforin 1 (pore forming protein)
- sheep(101110903) perforin 1 (pore forming protein)
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Perforin-1 Antibody, clone dG9 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
flow cytometry
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-Perforin-1 Antibody, clone 1H11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
flow cytometry
immunohistochemistry
western blot
flow cytometry
immunohistochemistry
western blot