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Merck

PPP2R3A

protein phosphatase 2, regulatory subunit B'', alpha

Sinónimos:
PPP2R3, PR130, PR72
Especie:
ID UniProtKB:
ID del gen:
  • Human(5523) Summary: This gene encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Jun 2010]
  • Mouse(235542) protein phosphatase 2, regulatory subunit B'', alpha
  • Rat(363122) protein phosphatase 2, regulatory subunit B'', alpha
  • chicken(424733) protein phosphatase 2, regulatory subunit B'', alpha
  • Horse(100053302) protein phosphatase 2, regulatory subunit B'', alpha
  • dog(485672) protein phosphatase 2, regulatory subunit B'', alpha
  • domestic cat(101083363) protein phosphatase 2, regulatory subunit B'', alpha
  • naked mole-rat(101697272) protein phosphatase 2, regulatory subunit B'', alpha
  • Domestic Rabbit(100353545) protein phosphatase 2, regulatory subunit B'', alpha
  • domestic guinea pig(100729010) protein phosphatase 2, regulatory subunit B'', alpha
  • cow(100851082) protein phosphatase 2, regulatory subunit B'', alpha
  • sheep(101114233) protein phosphatase 2, regulatory subunit B'', alpha

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Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Cantharidin, ,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PPP2R3A,
Especie
human