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Merck

PKD2

polycystic kidney disease 2 (autosomal dominant)

Sinónimos:
APKD2, PC2, PKD4, Pc-2, TRPP2
Especie:
ID UniProtKB:
ID del gen:
  • Human(5311) Summary: This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011]
  • Mouse(18764) polycystic kidney disease 2
  • Rat(498328) polycystic kidney disease 2 (autosomal dominant)
  • fruit fly(34651) Polycystic kidney disease gene-2
  • Zebrafish(432387) polycystic kidney disease 2
  • domestic cat(101098948) polycystic kidney disease 2 (autosomal dominant)
  • dog(487852) polycystic kidney disease 2 (autosomal dominant)
  • chicken(422585) polycystic kidney disease 2 (autosomal dominant)
  • cow(530393) polycystic kidney disease 2 (autosomal dominant)
  • sheep(101103569) polycystic kidney disease 2 (autosomal dominant)
  • domestic guinea pig(100714947) polycystic kidney disease 2 (autosomal dominant)
  • naked mole-rat(101726639) polycystic kidney disease 2 (autosomal dominant)
  • Domestic Rabbit(100008872) polycystic kidney disease 2 (autosomal dominant)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Polycystin-L Antibody, serum, Chemicon®,
Reactividad de especies
mouse
Aplicación
immunocytochemistry
immunohistochemistry

western blot
Anti-PKD2 Antibody, Upstate®, from rabbit,
Reactividad de especies
human
Aplicación
western blot
Anti-PKD2 Rabbit pAb, liquid, Calbiochem®,
Reactividad de especies
human
Aplicación
Anticuerpo anti-policistina -2, serum, Chemicon®,
Reactividad de especies
mouse
Aplicación
immunocytochemistry
immunohistochemistry

western blot

Proteins

Referencia del producto
Descripción
Especie
PKD2 Recombinant Human Protein, Active, 10 µg, Active, N-terminal His6 tagged, recombinant, full length, human PKD2, for use in Kinase Assays.,
Especie

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Pkd2,
Especie
mouse
MISSION® esiRNA, targeting human PKD2,
Especie
human