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Merck

PDHB

pyruvate dehydrogenase (lipoamide) beta

Sinónimos:
PDHBD, PDHE1-B, PHE1B
Especie:
ID UniProtKB:
ID del gen:
  • Human(5162) Summary: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]
  • Mouse(68263) pyruvate dehydrogenase (lipoamide) beta
  • Rat(289950) pyruvate dehydrogenase (lipoamide) beta
  • cow(613610) pyruvate dehydrogenase (lipoamide) beta
  • sheep(101121975) pyruvate dehydrogenase (lipoamide) beta
  • domestic guinea pig(100733476) pyruvate dehydrogenase (lipoamide) beta
  • naked mole-rat(101714134) pyruvate dehydrogenase (lipoamide) beta
  • Zebrafish(406428) pyruvate dehydrogenase (lipoamide) beta
  • Horse(100050581) pyruvate dehydrogenase (lipoamide) beta
  • domestic cat(101100374) pyruvate dehydrogenase (lipoamide) beta
  • dog(476574) pyruvate dehydrogenase (lipoamide) beta
  • chicken(416066) pyruvate dehydrogenase (lipoamide) beta

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PDHB antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

Kits

Referencia del producto
Descripción
Especie
Pyruvate Dehydrogenase Activity Assay Kit, sufficient for 100 colorimetric tests,
Especie
rat, mouse, human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PDHB,
Especie
human
MISSION® esiRNA, targeting mouse Pdhb,
Especie
mouse