Saltar al contenido
Merck

PADI1

peptidyl arginine deiminase, type I

Sinónimos:
HPAD10, PAD1, PDI, PDI1
Especie:
ID UniProtKB:
ID del gen:
  • Human(29943) Summary: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
  • Mouse(18599) peptidyl arginine deiminase, type I
  • Rat(54282) peptidyl arginine deiminase, type I
  • sheep(101108201) peptidyl arginine deiminase, type I
  • domestic guinea pig(100728246) peptidyl arginine deiminase, type I
  • naked mole-rat(101722077) peptidyl arginine deiminase, type I
  • chicken(428171) peptidyl arginine deiminase, type I
  • cow(618224) peptidyl arginine deiminase, type I
  • Horse(100049961) peptidyl arginine deiminase, type I
  • domestic cat(101085557) peptidyl arginine deiminase, type I
  • dog(608443) peptidyl arginine deiminase, type I

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Proteins

Referencia del producto
Descripción
Especie
PAD Cocktail, Active, recombinant,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PADI1,
Especie
human