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Merck

OGT

O-linked N-acetylglucosamine (GlcNAc) transferase

Sinónimos:
HRNT1, O-GLCNAC
Especie:
ID UniProtKB:
ID del gen:
  • Human(8473) Summary: This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
  • Mouse(108155) O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
  • Rat(26295) O-linked N-acetylglucosamine (GlcNAc) transferase
  • chicken(422203) O-linked N-acetylglucosamine (GlcNAc) transferase
  • dog(480955) O-linked N-acetylglucosamine (GlcNAc) transferase
  • domestic cat(101094162) O-linked N-acetylglucosamine (GlcNAc) transferase
  • cow(532053) O-linked N-acetylglucosamine (GlcNAc) transferase
  • Horse(100056148) O-linked N-acetylglucosamine (GlcNAc) transferase
  • sheep(101106996) O-linked N-acetylglucosamine (GlcNAc) transferase
  • Domestic Rabbit(100354727) O-linked N-acetylglucosamine (GlcNAc) transferase
  • domestic guinea pig(100728617) O-linked N-acetylglucosamine (GlcNAc) transferase

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-O- GlcNAc, clon CTD110.6, clone CTD110.6, from mouse,
Reactividad de especies
all
Aplicación
ELISA
immunoprecipitation (IP)

western blot
Anti-O-Linked N-Acetylglucosamine Antibody, clone RL2, clone RL2, from mouse,
Reactividad de especies
all
Aplicación
affinity binding assay
electron microscopy

immunocytochemistry

immunoprecipitation (IP)

western blot
Anticuerpo anti-O-GlcNAc, clon 9D1.E4(10), clone 9D1.E4(10), from mouse,
Reactividad de especies
human
Aplicación
western blot
Anti-OGT antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Ogt,
Especie
mouse
MISSION® esiRNA, targeting human OGT,
Especie
human