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Merck

NRGN

neurogranin (protein kinase C substrate, RC3)

Sinónimos:
RC3, hng
Especie:
ID UniProtKB:
ID del gen:
  • Human(4900) Summary: Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq, Jul 2008]
  • Mouse(64011) neurogranin
  • Rat(64356) neurogranin
  • domestic guinea pig(100722735) neurogranin (protein kinase C substrate, RC3)
  • naked mole-rat(101719402) neurogranin (protein kinase C substrate, RC3)
  • sheep(101107911) neurogranin (protein kinase C substrate, RC3)
  • chicken(768940) neurogranin (protein kinase C substrate, RC3)
  • cow(616955) neurogranin (protein kinase C substrate, RC3)
  • domestic cat(101080823) neurogranin (protein kinase C substrate, RC3)
  • dog(479401) neurogranin (protein kinase C substrate, RC3)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Neurogranin, from rabbit, purified by affinity chromatography,
Reactividad de especies
bovine, goat, human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-phospho-Neurogranin (Ser36)/Neuromodulin (Ser41) Antibody, serum, from rabbit,
Reactividad de especies
mouse, rat
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human NRGN,
Especie
human