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Merck

NRAS

neuroblastoma RAS viral (v-ras) oncogene homolog

Sinónimos:
ALPS4, N-ras, NRAS1, NS6
Especie:
ID UniProtKB:
ID del gen:
  • Human(4893) Summary: This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]
  • Mouse(18176) neuroblastoma ras oncogene
  • Rat(24605) neuroblastoma ras oncogene
  • Zebrafish(30380) neuroblastoma RAS viral (v-ras) oncogene homolog
  • cow(506322) neuroblastoma RAS viral (v-ras) oncogene homolog
  • dog(403872) neuroblastoma RAS viral (v-ras) oncogene homolog
  • chicken(419885) neuroblastoma RAS viral (v-ras) oncogene homolog
  • sheep(101102438) neuroblastoma RAS viral (v-ras) oncogene homolog
  • domestic guinea pig(100135584) neuroblastoma ras oncogene
  • naked mole-rat(101719269) neuroblastoma RAS viral (v-ras) oncogene homolog

Custom & Knockdown Gene Products

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-KRAS+HRAS+NRAS Antibody, clone 6S6F3, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
western blot
Anticuerpo anti-Ras, clon RAS10, clone RAS10, Upstate®, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
ELISA
flow cytometry

immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Ras Antibody, (K-, H-, N-), clone 9A11.2, clone 9A11.2, Upstate®, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-Ras Magnetic Bead Conjugate Antibody, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunoprecipitation (IP)
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse NRAS,
Especie
mouse
MISSION® esiRNA, targeting human NRAS,
Especie
human