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Merck

NFASC

neurofascin

Sinónimos:
NF, NRCAML
Especie:
ID UniProtKB:
ID del gen:
  • Human(23114) Summary: This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.[provided by RefSeq, May 2009]
  • Mouse(269116) neurofascin
  • Rat(116690) neurofascin
  • naked mole-rat(101716337) neurofascin
  • domestic guinea pig(100721545) neurofascin
  • sheep(101109290) neurofascin
  • chicken(419824) neurofascin
  • domestic cat(101083317) neurofascin
  • cow(512796) neurofascin
  • Horse(100054575) neurofascin
  • dog(488565) neurofascin

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Pan-Neurofascin Antibody, clone L11A/41, clone L11A/41, from mouse,
Reactividad de especies
rat
Aplicación
immunohistochemistry
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human NFASC,
Especie
human
MISSION® esiRNA, targeting mouse Nfasc,
Especie
mouse