NDUFV1
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
Sinónimos:
CI-51K, CI51KD, UQOR1
Especie:
Human NDUFV1 (4723), Mouse Ndufv1 (17995), Rat Ndufv1 (293655), Zebrafish ndufv1 (445291), chicken NDUFV1 (430210), dog NDUFV1 (476004), cow NDUFV1 (287014), domestic cat NDUFV1 (101093395), sheep NDUFV1 (101121129), naked mole-rat Ndufv1 (101726275)
ID UniProtKB:
ID del gen:
- Human(4723) Summary: The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]
- Mouse(17995) NADH dehydrogenase (ubiquinone) flavoprotein 1
- Rat(293655) NADH dehydrogenase (ubiquinone) flavoprotein 1
- Zebrafish(445291) NADH dehydrogenase (ubiquinone) flavoprotein 1
- chicken(430210) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- dog(476004) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- cow(287014) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- domestic cat(101093395) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- sheep(101121129) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- naked mole-rat(101726275) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
- domestic guinea pig(100725831) NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
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Small Molecule - Inhibitor
Referencia del producto
Descripción
Especie
1,1-Dimetilbiguanida hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
1,1-Dimetilbiguanida hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Especie
human
1,1-Dimetilbiguanida hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Especie
human