MBP
myelin basic protein
Sinónimos:
Especie:
Human MBP (4155), Mouse Mbp (17196), Rat Mbp (24547), chicken MBP (396217), domestic cat MBP (101096421), dog MBP (476160), cow MBP (618684), naked mole-rat Mbp (101702488), domestic guinea pig Mbp (100731253), sheep MBP (101109407)
ID UniProtKB:
ID del gen:
- Human(4155) Summary: The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008]
- Mouse(17196) myelin basic protein
- Rat(24547) myelin basic protein
- chicken(396217) myelin basic protein
- domestic cat(101096421) myelin basic protein
- dog(476160) myelin basic protein
- cow(618684) myelin basic protein
- naked mole-rat(101702488) myelin basic protein
- domestic guinea pig(100731253) myelin basic protein
- sheep(101109407) myelin basic protein
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Myelin Basic Protein Mouse mAb (SMI-99), liquid, clone SMI-99, Calbiochem®,
Reactividad de especies
guinea pig, mammals
Aplicación
Anti-phospho-MBP Antibody, clone P12, clone P12, Upstate®, from mouse,
Reactividad de especies
vertebrates
Aplicación
activity assay
western blot
western blot
Anti-Myelin Basic Protein Antibody, a.a. 36-50, clone 14, culture supernatant, clone 14, Chemicon®,
Reactividad de especies
mammals
Aplicación
ELISA
immunohistochemistry
immunohistochemistry
Anti-Myelin Basic Protein antibody produced in rabbit, ,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot
western blot
Anticuerpo anti-proteína básica de mielina, Chemicon®, from chicken,
Reactividad de especies
human, mouse
Aplicación
immunocytochemistry
immunohistochemistry
immunohistochemistry
Proteins
Referencia del producto
Descripción
Especie
Myelin Basic Protein bovine, ≥90% (SDS-PAGE), lyophilized powder, suitable for activity assay,
Especie
cow
Myelin Basic Protein from guinea pig brain, ≥80% (SDS-PAGE), lyophilized powder, from guinea pig brain,
Especie
domestic guinea pig
esiRNA
Referencia del producto
Descripción
Especie