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Merck

MAPK1

mitogen-activated protein kinase 1

Sinónimos:
ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk
Especie:
ID UniProtKB:
ID del gen:
  • Human(5594) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(26413) mitogen-activated protein kinase 1
  • Rat(116590) mitogen activated protein kinase 1
  • Zebrafish(360144) mitogen-activated protein kinase 1
  • domestic cat(101087614) mitogen-activated protein kinase 1
  • cow(327672) mitogen-activated protein kinase 1
  • dog(477575) mitogen-activated protein kinase 1
  • chicken(373953) mitogen-activated protein kinase 1
  • sheep(101115485) mitogen-activated protein kinase 1
  • domestic guinea pig(100715180) mitogen-activated protein kinase 1
  • naked mole-rat(101706099) mitogen-activated protein kinase 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-MAPK 1/2 Antibody, from rabbit,
Reactividad de especies
bovine, canine, human, mouse, rat
Aplicación
immunocytochemistry
immunoprecipitation (IP)

western blot
Milli-Mark® Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate, Milli-Mark®, from rabbit,
Reactividad de especies
human
Aplicación
flow cytometry
Anti-phospho-MAP Kinase1/2 Antibody, clone 12D4, Upstate®, from mouse,
Reactividad de especies
avian, canine, human, mouse, rat
Aplicación
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti- ERK2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
Anti-MAPK1 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, canine, goat, guinea pig, horse, human, mouse, rabbit, rat, zebrafish
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Adenina, ≥99%,
Especie
human, rat, mouse
Adenina, BioReagent, suitable for cell culture,
Especie
human, rat, mouse
Adenina, BioReagent, suitable for plant cell culture, ≥99%,
Especie
human, rat, mouse

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human MAPK1,
Especie
human