LMAN1
lectin, mannose-binding, 1
ERGIC-53, ERGIC53, F5F8D, FMFD1, MCFD1, MR60, gp58
Human LMAN1 (3998), Mouse Lman1 (70361), Rat Lman1 (116666), Zebrafish lman1 (559775), chicken LMAN1 (426849), cow LMAN1 (511649), Horse LMAN1 (100050262), domestic cat LMAN1 (101080833), dog LMAN1 (476186), sheep LMAN1 (101117293) ...Más
- Human(3998) Summary: The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq, Jul 2008]
- Mouse(70361) lectin, mannose-binding, 1
- Rat(116666) lectin, mannose-binding, 1
- Zebrafish(559775) lectin, mannose-binding, 1
- chicken(426849) lectin, mannose-binding, 1
- cow(511649) lectin, mannose-binding, 1
- Horse(100050262) lectin, mannose-binding, 1
- domestic cat(101080833) lectin, mannose-binding, 1
- dog(476186) lectin, mannose-binding, 1
- sheep(101117293) lectin, mannose-binding, 1
- Domestic Rabbit(100354112) lectin, mannose-binding, 1
- domestic guinea pig(100728262) lectin, mannose-binding, 1
- naked mole-rat(101723407) lectin, mannose-binding, 1
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