LECT1
leukocyte cell derived chemotaxin 1
Sinónimos:
BRICD3, CHM-I, CHM1, MYETS1
Especie:
Human LECT1 (11061), Mouse Lect1 (16840), Rat Lect1 (81512), Zebrafish lect1 (791772), cow LECT1 (281683), Horse LECT1 (100051618), domestic cat LECT1 (101091335), dog LECT1 (609613), chicken LECT1 (395600), sheep LECT1 (101106181) ...Más
ID UniProtKB:
ID del gen:
- Human(11061) Summary: This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(16840) leukocyte cell derived chemotaxin 1
- Rat(81512) leukocyte cell derived chemotaxin 1
- Zebrafish(791772) leukocyte cell derived chemotaxin 1
- cow(281683) leukocyte cell derived chemotaxin 1
- Horse(100051618) leukocyte cell derived chemotaxin 1
- domestic cat(101091335) leukocyte cell derived chemotaxin 1
- dog(609613) leukocyte cell derived chemotaxin 1
- chicken(395600) leukocyte cell derived chemotaxin 1
- sheep(101106181) leukocyte cell derived chemotaxin 1
- domestic guinea pig(100734572) leukocyte cell derived chemotaxin 1
- naked mole-rat(101703802) leukocyte cell derived chemotaxin 1
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