KIFAP3
kinesin-associated protein 3
Sinónimos:
FLA3, KAP-1, KAP-3, KAP3, SMAP, Smg-GDS, dJ190I16.1
Especie:
Human KIFAP3 (22920), Mouse Kifap3 (16579), Rat Kifap3 (289168), chicken KIFAP3 (424395), cow KIFAP3 (518402), Horse KIFAP3 (100059088), domestic cat KIFAP3 (101084337), dog KIFAP3 (100685317), domestic guinea pig Kifap3 (100718672), naked mole-rat Kifap3 (101721676) ...Más
ID UniProtKB:
ID del gen:
- Human(22920) Summary: The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
- Mouse(16579) kinesin-associated protein 3
- Rat(289168) kinesin-associated protein 3
- chicken(424395) kinesin-associated protein 3
- cow(518402) kinesin-associated protein 3
- Horse(100059088) kinesin-associated protein 3
- domestic cat(101084337) kinesin-associated protein 3
- dog(100685317) kinesin-associated protein 3
- domestic guinea pig(100718672) kinesin-associated protein 3
- naked mole-rat(101721676) kinesin-associated protein 3
- sheep(101102827) kinesin-associated protein 3
- Domestic Rabbit(100345771) kinesin-associated protein 3
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Antibodies
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Aplicación
Anti-KIFAP3 Antibody, clone 1S7J7, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
western blot
western blot
esiRNA
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