KDR
kinase insert domain receptor (a type III receptor tyrosine kinase)
Sinónimos:
CD309, FLK1, VEGFR, VEGFR2
Especie:
Human KDR (3791), Mouse Kdr (16542), Rat Kdr (25589), Goat KDR (100860836), sheep KDR (443087), Domestic Rabbit KDR (100008607), domestic guinea pig Kdr (100726761), naked mole-rat Kdr (101726029), Zebrafish kdr (554230), cow KDR (407170) ...Más
ID UniProtKB:
ID del gen:
- Human(3791) Summary: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
- Mouse(16542) kinase insert domain protein receptor
- Rat(25589) kinase insert domain receptor
- Goat(100860836) kinase insert domain receptor (a type III receptor tyrosine kinase)
- sheep(443087) vascular endothelial growth factor receptor-2
- Domestic Rabbit(100008607) kinase insert domain receptor (a type III receptor tyrosine kinase)
- domestic guinea pig(100726761) kinase insert domain receptor (a type III receptor tyrosine kinase)
- naked mole-rat(101726029) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Zebrafish(554230) kinase insert domain receptor (a type III receptor tyrosine kinase)
- cow(407170) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Horse(100033959) kinase insert domain receptor (a type III receptor tyrosine kinase)
- domestic cat(101090260) kinase insert domain receptor (a type III receptor tyrosine kinase)
- dog(482154) kinase insert domain receptor (a type III receptor tyrosine kinase)
- chicken(395323) kinase insert domain receptor (a type III receptor tyrosine kinase)
- Thale Cress(839585) basic helix-loop-helix protein KIDARI
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-KDR/Flk-1/VEGFR2 Antibody, clone CH-11, clone CH-11, Upstate®, from mouse,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-VEGFR-2 Antibody, clone 3E21 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-p-VEGFR2 (Tyr1059) Antibody, clone 4C22-H1 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse, rat
Aplicación
immunocytochemistry
inhibition assay
western blot
inhibition assay
western blot
Anti-VEGFR-2 Antibody, clone 3C21 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Anti-phospho-KDR/Flk-1/VEGFR2 (Tyr1214) Antibody, Upstate®, from rabbit,
Reactividad de especies
human, mouse
Aplicación
western blot
Small Molecule - Inhibitor
Referencia del producto
Descripción
Especie
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
Especie
human
Proteins
Referencia del producto
Descripción
Especie
KDR Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant, human KDR amino acids 790-end,
for use in Kinase Assays.,
for use in Kinase Assays.,
Especie
human
VEGF Receptor-2 (Flk-1, KDR)/Fc Chimera human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Especie
human