Saltar al contenido
Merck

IL7R

interleukin 7 receptor

Sinónimos:
CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
Especie:
ID UniProtKB:
ID del gen:
  • Human(3575) Summary: The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq, Jul 2008]
  • Mouse(16197) interleukin 7 receptor
  • Rat(294797) interleukin 7 receptor
  • sheep(101111126) interleukin 7 receptor
  • Domestic Rabbit(100343726) interleukin 7 receptor
  • domestic guinea pig(100714027) interleukin 7 receptor
  • naked mole-rat(101710077) interleukin 7 receptor
  • Zebrafish(100134973) interleukin 7 receptor
  • dog(612582) interleukin 7 receptor
  • domestic cat(101100697) interleukin 7 receptor
  • Horse(100034169) interleukin 7 receptor
  • cow(521554) interleukin 7 receptor
  • chicken(426054) interleukin 7 receptor

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-CD127 (IL-7Ra) Antibody (mouse), FITC, clone A7R34, clone A7R34, 0.5 mg/mL, from rat,
Reactividad de especies
mouse
Aplicación
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Anticuerpo anti-CD127 (IL-7Ra) (ratón), PE-Cy7, clon A7R34, clone A7R34, 0.2 mg/mL, from rat,
Reactividad de especies
mouse
Aplicación
flow cytometry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)
Anticuerpo anti-CD127 (IL-7Ra) (ratón), biotina, clon A7R34, clone A7R34, 0.5 mg/mL, from rat,
Reactividad de especies
mouse
Aplicación
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Anti-CD127 (IL-7Ra) Antibody (mouse), APC, clone A7R34, clone A7R34, 0.2 mg/mL, from rat,
Reactividad de especies
mouse
Aplicación
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Anti-CD127 (IL-7Ra) Antibody (mouse), FITC, clone A7R34, clone A7R34, 0.5 mg/mL, from rat,
Reactividad de especies
mouse
Aplicación
flow cytometry
immunohistochemistry

immunoprecipitation (IP)

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human IL7R,
Especie
human