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Merck

IL2RA

interleukin 2 receptor, alpha

Sinónimos:
CD25, IDDM10, IL2R, TCGFR
Especie:
ID UniProtKB:
ID del gen:
  • Human(3559) Summary: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009]
  • Mouse(16184) interleukin 2 receptor, alpha chain
  • Rat(25704) interleukin 2 receptor, alpha
  • chicken(395294) interleukin 2 receptor, alpha
  • dog(403870) interleukin 2 receptor, alpha
  • cow(281861) interleukin 2 receptor, alpha
  • Horse(100070292) interleukin 2 receptor, alpha
  • domestic cat(493953) interleukin 2 receptor, alpha
  • sheep(443435) interleukin 2 receptor, alpha
  • domestic guinea pig(100715332) interleukin 2 receptor, alpha
  • naked mole-rat(101696651) interleukin 2 receptor, alpha

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-CD25 PE-Cyanine7 produced in mouse, ,
Reactividad de especies
human
Aplicación
flow cytometry
Anti-IL-2 Rα Antibody, clone 7G7/B6, clone 7G7/B6, Upstate®, from mouse,
Reactividad de especies
human
Aplicación
dot blot
immunocytochemistry
Anti-CD25 Antibody (mouse), APC, clone PC61.5, clone PC61.5, 0.2 mg/mL, from rat,
Reactividad de especies
mouse
Aplicación
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Anti-CD25 Antibody, clone 7D4, ,
Reactividad de especies
mouse
Aplicación
flow cytometry
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

inhibition assay

radioimmunoassay
Anti-CD25 Antibody (mouse), APC, clone PC61.5, clone PC61.5, 0.2 mg/mL, from rat,
Reactividad de especies
mouse
Aplicación
flow cytometry
immunohistochemistry

immunoprecipitation (IP)

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human IL2RA,
Especie
human