IL1B
interleukin 1, beta
IL-1, IL1-BETA, IL1F2
Human IL1B (3553), Mouse Il1b (16176), Rat Il1b (24494), Zebrafish il1b (557541), domestic cat IL1B (768274), cow IL1B (281251), Horse IL1B (100034237), dog IL1B (403974), Zebrafish il1b (405770), chicken IL1B (395196) ...Más
- Human(3553) Summary: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
- Mouse(16176) interleukin 1 beta
- Rat(24494) interleukin 1 beta
- Zebrafish(557541) interleukin 1, beta
- domestic cat(768274) interleukin 1, beta
- cow(281251) interleukin 1, beta
- Horse(100034237) interleukin 1, beta
- dog(403974) interleukin 1, beta
- Zebrafish(405770) interleukin 1, beta
- chicken(395196) interleukin 1, beta
- Goat(100860816) interleukin 1, beta
- Domestic Rabbit(100008990) interleukin 1, beta
- domestic guinea pig(100135556) interleukin 1 beta
- naked mole-rat(101704309) interleukin 1, beta
Custom & Knockdown Gene Products
siRNA
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shRNA
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Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Antagonist
Antibodies
Anti-Interleukin-1 beta (IL-1B) Antibody, clone 4A7, clone AB34_41.4H12.4A7, from mouse,
human
western blot
Anti-IL1B (N-terminal) antibody produced in rabbit, affinity isolated antibody,
canine, horse, human, mouse, rabbit
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Proteins
Interleukin-1β from rat, IL-1β, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
rat