IL18BP
interleukin 18 binding protein
Sinónimos:
IL18BPa
Especie:
Human IL18BP (10068), Mouse Il18bp (16068), Rat Il18bp (84388), domestic guinea pig Il18bp (100714819), naked mole-rat Il18bp (101721919), sheep IL18BP (101118983), cow IL18BP (617470), domestic cat IL18BP (101096599), dog IL18BP (476818)
ID UniProtKB:
ID del gen:
- Human(10068) Summary: The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
- Mouse(16068) interleukin 18 binding protein
- Rat(84388) interleukin 18 binding protein
- domestic guinea pig(100714819) interleukin 18 binding protein
- naked mole-rat(101721919) interleukin 18 binding protein
- sheep(101118983) interleukin 18 binding protein
- cow(617470) interleukin 18 binding protein
- domestic cat(101096599) interleukin 18 binding protein
- dog(476818) interleukin 18 binding protein
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