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Merck

IGF2R

insulin-like growth factor 2 receptor

Sinónimos:
CD222, CIMPR, M6P-R, MPR1, MPRI
Especie:
ID UniProtKB:
ID del gen:
  • Human(3482) Summary: This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele. [provided by RefSeq, Apr 2013]
  • Mouse(16004) insulin-like growth factor 2 receptor
  • Rat(25151) insulin-like growth factor 2 receptor
  • Goat(100860744) insulin-like growth factor 2 receptor
  • domestic guinea pig(100725901) insulin-like growth factor 2 receptor
  • naked mole-rat(101707470) insulin-like growth factor 2 receptor
  • Zebrafish(557061) insulin-like growth factor 2 receptor
  • domestic cat(100500935) insulin-like growth factor 2 receptor
  • Horse(100058539) insulin-like growth factor 2 receptor
  • cow(281849) insulin-like growth factor 2 receptor
  • dog(484067) insulin-like growth factor 2 receptor
  • chicken(395817) insulin-like growth factor 2 receptor

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-IGF-2R/CD222 Antibody, clone 2O9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey
Aplicación
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-MPR300/IGF-2R/CD222 Antibody, clone 2C2, clone 2C2, from mouse,
Reactividad de especies
human
Aplicación
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-Cation-independent M6PR (IGF2R) Antibody, clone 4J4A3, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunofluorescence
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Igf2r,
Especie
mouse
MISSION® esiRNA, targeting human IGF2R,
Especie
human