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Merck

GZMB

granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)

Sinónimos:
CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
Especie:
Human GZMB (3002), Mouse Gzmb (14939), Rat Gzmb (171528), dog GZMB (490630), cow GZMB (508646), cow GZMB (281731), Horse GZMB (100033978), domestic cat GZMB (100127106), domestic guinea pig Gzmb (100736180), naked mole-rat Gzmb (101702156)
ID UniProtKB:
P10144, Q8N1D2, Q9UCC1
ID del gen:
  • Human(3002) Summary: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008]
  • Mouse(14939) granzyme B
  • Rat(171528) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • dog(490630) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • cow(508646) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • cow(281731) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • Horse(100033978) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • domestic cat(100127106) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • domestic guinea pig(100736180) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • naked mole-rat(101702156) granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
MAB3070
Anti-Granzyme B Antibody, clone GrB-7, culture supernatant, clone GrB-7, Chemicon®,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
ZRB2736
Anti-Granzyme B Antibody, clone 3M4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
ELISA
affinity binding assay
flow cytometry
western blot

Proteins

Referencia del producto
Descripción
Especie
SRE0021
Granzyme B human, recombinant, expressed in insect cells, ≥90% (SDS-PAGE),
Especie
human
SRP3202
Granzyme B from mouse, recombinant, expressed in Hi-5 Insect cells, ≥97% (SDS-PAGE), ≥97% (HPLC), suitable for cell culture,
Especie
mouse

esiRNA

Referencia del producto
Descripción
Especie
EHU106641
MISSION® esiRNA, targeting human GZMB,
Especie
human

Small Molecule - Substrate

Referencia del producto
Descripción
Especie
A6470
N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide, ≥97% (HPLC), powder,
Especie
rat, mouse, human
A9968
N-Acetyl-Ile-Glu-Thr-Asp-p-nitroanilide, ≥95%,
Especie
rat, mouse, human
A6220
N-Acetyl-Ile-Glu-Pro-Asp-7-amido-4-methylcoumarin, ≥97% (HPLC), powder,
Especie
rat, mouse, human
A4188
N-Acetyl-Ile-Glu-Thr-Asp-7-Amido-4-methylcoumarin, ≥97% (HPLC), powder,
Especie
rat, mouse, human