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Merck

GDF5

growth differentiation factor 5

Sinónimos:
BDA1C, BMP14, CDMP1, LAP4, OS5, SYM1B, SYNS2
Especie:
ID UniProtKB:
ID del gen:
  • Human(8200) Summary: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development. [provided by RefSeq, Jul 2008]
  • Mouse(14563) growth differentiation factor 5
  • Rat(252835) growth differentiation factor 5
  • Zebrafish(30195) growth differentiation factor 5
  • chicken(374249) growth differentiation factor 5
  • dog(485850) growth differentiation factor 5
  • Horse(100034228) growth differentiation factor 5
  • cow(539559) growth differentiation factor 5
  • domestic cat(101081533) growth differentiation factor 5
  • naked mole-rat(101696976) growth differentiation factor 5
  • domestic guinea pig(100723808) growth differentiation factor 5
  • sheep(101116499) growth differentiation factor 5
  • Domestic Rabbit(100328897) growth differentiation factor 5

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Proteins

Referencia del producto
Descripción
Especie
BMP-14 (GDF-5/CDMP-1) human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Especie
human
GDF-5 mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Especie
mouse

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Gdf5,
Especie
mouse
MISSION® esiRNA, targeting human GDF5,
Especie
human