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Merck

GABRG3

gamma-aminobutyric acid (GABA) A receptor, gamma 3

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(2567) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
  • Mouse(14407) gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
  • Rat(79211) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • domestic guinea pig(100729690) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • naked mole-rat(101712623) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • sheep(101108521) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • Zebrafish(567057) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • cow(613670) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • domestic cat(101094182) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • dog(488685) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • chicken(770097) gamma-aminobutyric acid (GABA) A receptor, gamma 3

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Especie
human

Small Molecule - Allosteric Modulator

Referencia del producto
Descripción
Especie
Propofol, British Pharmacopoeia (BP) Reference Standard,
Especie
human
Ganaxolone, ≥98% (HPLC), solid,
Especie
human, mouse
2,6-Diisopropylphenol, 97%,
Especie
human
Acamprosate calcium, ≥98% (HPLC), powder,
Especie
human
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Ganaxolone, ≥98% (HPLC), solid,
Especie
human, mouse
2,6-Diisopropylphenol, 97%,
Especie
human
Acamprosate calcium, ≥98% (HPLC), powder,
Especie
human
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Especie
human
Acamprosate calcium, British Pharmacopoeia (BP) Reference Standard,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human GABRG3,
Especie
human