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Merck

FGG

fibrinogen gamma chain

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(2266) Summary: The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(99571) fibrinogen gamma chain
  • Rat(24367) fibrinogen gamma chain
  • Zebrafish(406327) fibrinogen, gamma polypeptide
  • dog(475474) fibrinogen gamma chain
  • cow(280792) fibrinogen gamma chain
  • Horse(100147221) fibrinogen gamma chain
  • domestic cat(101092680) fibrinogen gamma chain
  • chicken(395837) fibrinogen gamma chain
  • Domestic Rabbit(100351591) fibrinogen gamma chain
  • domestic guinea pig(100720373) fibrinogen gamma chain
  • naked mole-rat(101696987) fibrinogen gamma chain

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-FGG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot

Proteins

Referencia del producto
Descripción
Especie
Fibrinogen from human plasma, 50-70% protein (≥80% of protein is clottable),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human FGG,
Especie
human
MISSION® esiRNA, targeting mouse Fgg,
Especie
mouse