EGFR
epidermal growth factor receptor
Sinónimos:
ERBB, ERBB1, HER1, PIG61, mENA
Especie:
Human EGFR (1956), Mouse Egfr (13649), Rat Egfr (24329), fruit fly Egfr (37455), cow EGFR (407217), Horse EGFR (100067755), domestic cat EGFR (100510799), dog EGFR (404306), chicken EGFR (396494), domestic guinea pig Egfr (100725363) ...Más
ID UniProtKB:
ID del gen:
- Human(1956) Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
- Mouse(13649) epidermal growth factor receptor
- Rat(24329) epidermal growth factor receptor
- fruit fly(37455) Epidermal growth factor receptor
- cow(407217) epidermal growth factor receptor
- Horse(100067755) epidermal growth factor receptor
- domestic cat(100510799) epidermal growth factor receptor
- dog(404306) epidermal growth factor receptor
- chicken(396494) epidermal growth factor receptor
- domestic guinea pig(100725363) epidermal growth factor receptor
- naked mole-rat(101723771) epidermal growth factor receptor
- sheep(780479) epidermal growth factor receptor
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Small Molecule - Antagonist
Antibodies
Product Number
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-EGFR PE produced in mouse, ,
Reactividad de especies
horse
Aplicación
flow cytometry
Anti-EGFRvIII Antibody, clone DH8.3, clone DH8.3, from mouse,
Reactividad de especies
human
Aplicación
ELISA
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-EGFR Antibody, clone LA22, clone LA22, Upstate®, from mouse,
Reactividad de especies
human
Aplicación
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-EGFR Antibody, neutralizing, clone LA1, clone LA1, Upstate®, from mouse,
Reactividad de especies
human
Aplicación
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
neutralization
western blot
immunohistochemistry
immunoprecipitation (IP)
neutralization
western blot
Anti-EGFR Antibody, clone 528 (Azide-free), clone 528, from mouse,
Reactividad de especies
human
Aplicación
immunoprecipitation (IP)
neutralization
neutralization
Small Molecule - Inhibitor
Proteins
Product Number
Descripción
Especie
Epidermal Growth Factor Receptor human, lyophilized powder, ≥15,000 units/mg protein (Bradford),
Especie
human
EGF-receptor human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Especie
human
Epidermal Growth Factor Receptor human, buffered aqueous glycerol solution, 5,000-30,000 units/mg protein (Lowry),
Especie
human