EGFR
epidermal growth factor receptor
Sinónimos:
ERBB, ERBB1, HER1, PIG61, mENA
Especie:
Human EGFR (1956), Mouse Egfr (13649), Rat Egfr (24329), fruit fly Egfr (37455), cow EGFR (407217), Horse EGFR (100067755), domestic cat EGFR (100510799), dog EGFR (404306), chicken EGFR (396494), domestic guinea pig Egfr (100725363) ...Más
ID UniProtKB:
ID del gen:
- Human(1956) Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
- Mouse(13649) epidermal growth factor receptor
- Rat(24329) epidermal growth factor receptor
- fruit fly(37455) Epidermal growth factor receptor
- cow(407217) epidermal growth factor receptor
- Horse(100067755) epidermal growth factor receptor
- domestic cat(100510799) epidermal growth factor receptor
- dog(404306) epidermal growth factor receptor
- chicken(396494) epidermal growth factor receptor
- domestic guinea pig(100725363) epidermal growth factor receptor
- naked mole-rat(101723771) epidermal growth factor receptor
- sheep(780479) epidermal growth factor receptor
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Antagonist
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-EGFR PE produced in mouse, ,
Reactividad de especies
horse
Aplicación
flow cytometry
Anti-EGFRvIII Antibody, clone DH8.3, clone DH8.3, from mouse,
Reactividad de especies
human
Aplicación
ELISA
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-EGFR Antibody, clone LA22, clone LA22, Upstate®, from mouse,
Reactividad de especies
human
Aplicación
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-EGFR Antibody, neutralizing, clone LA1, clone LA1, Upstate®, from mouse,
Reactividad de especies
human
Aplicación
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
neutralization
western blot
immunohistochemistry
immunoprecipitation (IP)
neutralization
western blot
Anti-Phospho-EGFR (Tyr1068) Antibody, clone 3F4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey
Aplicación
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
Referencia del producto
Descripción
Especie
Epidermal Growth Factor Receptor human, lyophilized powder, ≥15,000 units/mg protein (Bradford),
Especie
human
EGF-receptor human, recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Especie
human
Epidermal Growth Factor Receptor human, buffered aqueous glycerol solution, 5,000-30,000 units/mg protein (Lowry),
Especie
human