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Merck

DDR1

discoidin domain receptor tyrosine kinase 1

Sinónimos:
CAK, CD167, DDR, EDDR1, HGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE
Especie:
ID UniProtKB:
ID del gen:
  • Human(780) Summary: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(12305) discoidin domain receptor family, member 1
  • Rat(25678) discoidin domain receptor tyrosine kinase 1
  • Zebrafish(100007346) discoidin domain receptor family, member 1
  • cow(534092) discoidin domain receptor tyrosine kinase 1
  • Horse(100050861) discoidin domain receptor tyrosine kinase 1
  • domestic cat(101096728) discoidin domain receptor tyrosine kinase 1
  • dog(474832) discoidin domain receptor tyrosine kinase 1
  • domestic guinea pig(100725492) discoidin domain receptor tyrosine kinase 1
  • naked mole-rat(101699683) discoidin domain receptor tyrosine kinase 1
  • sheep(101104279) discoidin domain receptor tyrosine kinase 1

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Antibodies

Product Number
Descripción
Reactividad de especies
Aplicación
Anti-CD167a/DDR1 Antibody, clone 1D11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, human, monkey, mouse, porcine, rat
Aplicación
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot

esiRNA

Product Number
Descripción
Especie
MISSION® esiRNA, targeting mouse Ddr1,
Especie
mouse
MISSION® esiRNA, targeting human DDR1,
Especie
human