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Merck

DDC

dopa decarboxylase (aromatic L-amino acid decarboxylase)

Sinónimos:
AADC
Especie:
ID UniProtKB:
ID del gen:
  • Human(1644) Summary: The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011]
  • Mouse(13195) dopa decarboxylase
  • Rat(24311) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • domestic guinea pig(100135516) dopa decarboxylase
  • naked mole-rat(101697555) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • sheep(101106765) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • Zebrafish(406651) dopa decarboxylase
  • chicken(420947) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • fruit fly(35190) Dopa decarboxylase
  • dog(606852) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • cow(280762) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • Horse(100052557) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • domestic cat(101082989) dopa decarboxylase (aromatic L-amino acid decarboxylase)

Custom & Knockdown Gene Products

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Dopa Decarboxylase Antibody, Chemicon®, from rabbit,
Reactividad de especies
canine, human, sheep
Aplicación
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Benserazide hydrochloride, ≥98% (HPLC), solid,
Especie
human
S-(−)-Carbidopa, ≥98% (TLC), powder,
Especie
human
Carbidopa, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
Benserazide for peak identification A, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Carbidopa, European Pharmacopoeia (EP) Reference Standard,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Ddc,
Especie
mouse