DAZL
deleted in azoospermia-like
Sinónimos:
DAZH, DAZL1, DAZLA, SPGYLA
Especie:
Human DAZL (1618), Mouse Dazl (13164), Rat Dazl (680486), Zebrafish dazl (58039), chicken DAZL (374054), cow DAZL (530116), dog DAZL (477055), sheep DAZL (100885769), domestic guinea pig Dazl (100722319), naked mole-rat Dazl (101723796)
ID UniProtKB:
ID del gen:
- Human(1618) Summary: The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
- Mouse(13164) deleted in azoospermia-like
- Rat(680486) deleted in azoospermia-like
- Zebrafish(58039) deleted in azoospermia-like
- chicken(374054) deleted in azoospermia-like
- cow(530116) deleted in azoospermia-like
- dog(477055) deleted in azoospermia-like
- sheep(100885769) deleted in azoospermia-like
- domestic guinea pig(100722319) deleted in azoospermia-like
- naked mole-rat(101723796) deleted in azoospermia-like
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