COL17A1
collagen, type XVII, alpha 1
BA16H23.2, BP180, BPA-2, BPAG2, LAD-1
Human COL17A1 (1308), Mouse Col17a1 (12821), Rat Col17a1 (294027), domestic guinea pig Col17a1 (100721447), naked mole-rat Col17a1 (101710063), sheep COL17A1 (101116007), chicken COL17A1 (396503), dog COL17A1 (403739), domestic cat COL17A1 (101096849), cow COL17A1 (513804)
- Human(1308) Summary: This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008]
- Mouse(12821) collagen, type XVII, alpha 1
- Rat(294027) collagen, type XVII, alpha 1
- domestic guinea pig(100721447) collagen, type XVII, alpha 1
- naked mole-rat(101710063) collagen, type XVII, alpha 1
- sheep(101116007) collagen, type XVII, alpha 1
- chicken(396503) collagen, type XVII, alpha 1
- dog(403739) collagen, type XVII, alpha 1
- domestic cat(101096849) collagen, type XVII, alpha 1
- cow(513804) collagen, type XVII, alpha 1
- Horse(100069671) collagen, type XVII, alpha 1
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Antibodies
Anti-Collagen XVII/COL17A1 Antibody, clone 8W2C8, Rabbit Monoclonal, ,
human
immunohistochemistry
western blot
western blot