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Merck

CHUK

conserved helix-loop-helix ubiquitous kinase

Sinónimos:
IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16
Especie:
Human CHUK (1147), Mouse Chuk (12675), Rat Chuk (309361), Zebrafish chuk (393287), cow CHUK (281073), Horse CHUK (100070393), dog CHUK (477796), chicken CHUK (423669), domestic cat CHUK (101095617), sheep CHUK (101111143) ...Más
ID UniProtKB:
O15111, O14666, Q13132, Q5W0I4, Q92467
ID del gen:
  • Human(1147) Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008]
  • Mouse(12675) conserved helix-loop-helix ubiquitous kinase
  • Rat(309361) conserved helix-loop-helix ubiquitous kinase
  • Zebrafish(393287) conserved helix-loop-helix ubiquitous kinase
  • cow(281073) conserved helix-loop-helix ubiquitous kinase
  • Horse(100070393) conserved helix-loop-helix ubiquitous kinase
  • dog(477796) conserved helix-loop-helix ubiquitous kinase
  • chicken(423669) conserved helix-loop-helix ubiquitous kinase
  • domestic cat(101095617) conserved helix-loop-helix ubiquitous kinase
  • sheep(101111143) conserved helix-loop-helix ubiquitous kinase
  • domestic guinea pig(100726357) conserved helix-loop-helix ubiquitous kinase
  • naked mole-rat(101719306) conserved helix-loop-helix ubiquitous kinase

Custom & Knockdown Gene Products

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
SAB5702171
Anti-IKKα Antibody, clone 2M10E3, Rabbit Monoclonal, ,
Reactividad de especies
mouse
Aplicación
western blot
ZRB1673
Anti-p-IKKα/β-Ser176/180 Antibody, clone 2G2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, canine, feline, human, monkey, mouse, porcine, rat
Aplicación
affinity binding assay
immunohistochemistry
inhibition assay
western blot
MABF222
Anticuerpo anti-IKKa (p45), clon 881H3, clone 881H3, from mouse,
Reactividad de especies
human
Aplicación
immunohistochemistry
immunoprecipitation (IP)
western blot
05-536
Anticuerpo anti-IKKα, clon 14A231, clone 14A231, Upstate®, from mouse,
Reactividad de especies
human, monkey, mouse
Aplicación
western blot
OP133
Anti-IKKα Mouse mAb (14A231), liquid, clone 14A231, Calbiochem®,
Reactividad de especies
human, monkey, mouse
Aplicación

Proteins

Referencia del producto
Descripción
Especie
14-461-M
IKKα Protein, active, 10 µg, Active, recombinant full-length human IKKα, containing an N-terminal GST-tag, for use in Kinase Assays.,
Especie
human
SRP5040
IKK α , active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EMU041031
MISSION® esiRNA, targeting mouse Chuk,
Especie
mouse
EHU229471
MISSION® esiRNA, targeting human CHUK,
Especie
human

Small Molecule - Substrate

Referencia del producto
Descripción
Especie
12-459
IKK Substrate Peptide, ,
Especie
human