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Merck

CHRNA3

cholinergic receptor, nicotinic, alpha 3 (neuronal)

Sinónimos:
LNCR2, NACHRA3, PAOD2
Especie:
ID UniProtKB:
ID del gen:
  • Human(1136) Summary: This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
  • Mouse(110834) cholinergic receptor, nicotinic, alpha polypeptide 3
  • Rat(25101) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • Zebrafish(568467) cholinergic receptor, nicotinic, alpha 3
  • dog(482111) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • domestic cat(100037403) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • cow(282702) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • chicken(386578) cholinergic receptor, nicotinic, alpha 3
  • naked mole-rat(101701279) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • domestic guinea pig(100730977) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • sheep(101123239) cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • Domestic Rabbit(100342666) cholinergic receptor, nicotinic, alpha 3 (neuronal)

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
(±)-Nicotine, ≥99% (TLC), liquid,
Especie
human, rat
Carbamoylcholine chloride, ≥98% (titration), crystalline,
Especie
human, mouse, rat
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Especie
human, mouse, rat
(−)-Nicotina, ≥99% (GC), liquid,
Especie
human, mouse, rat
Decamethonium bromide, crystalline,
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Cytisine, ≥99%, powder,
Especie
rat
(±)-Nicotine, ≥99% (TLC), liquid,
Especie
human, rat
Carbamoylcholine chloride, ≥98% (titration), crystalline,
Especie
human, mouse, rat
Mecamylamine hydrochloride, ,
Especie
human
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Especie
human, mouse, rat

Small Molecule - Blocker

Referencia del producto
Descripción
Especie
Tetraethylammonium chloride, ≥98% (titration),
Especie
human
Hexamethonium bromide, ,
Especie
human
Hexamethonium chloride, solid (hygroscopic),
Especie
human
Kynurenic acid, ≥98%,
Especie
rat, human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human CHRNA3,
Especie
human
MISSION® esiRNA, targeting mouse Chrna3,
Especie
mouse