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Merck

CHRM4

cholinergic receptor, muscarinic 4

Sinónimos:
HM4, M4R
Especie:
Human CHRM4 (1132), Mouse Chrm4 (12672), Rat Chrm4 (25111), chicken CHRM4 (423195), cow CHRM4 (512928), domestic cat CHRM4 (101088360), dog CHRM4 (611314), sheep CHRM4 (101114554), Domestic Rabbit CHRM4 (100008791), domestic guinea pig Chrm4 (100714736)
ID UniProtKB:
P08173, B2RPP4, Q0VD60, Q4VBK7
ID del gen:
  • Human(1132) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008]
  • Mouse(12672) cholinergic receptor, muscarinic 4
  • Rat(25111) cholinergic receptor, muscarinic 4
  • chicken(423195) cholinergic receptor, muscarinic 4
  • cow(512928) cholinergic receptor, muscarinic 4
  • domestic cat(101088360) cholinergic receptor, muscarinic 4
  • dog(611314) cholinergic receptor, muscarinic 4
  • sheep(101114554) cholinergic receptor, muscarinic 4
  • Domestic Rabbit(100008791) cholinergic receptor, muscarinic 4
  • domestic guinea pig(100714736) cholinergic receptor, muscarinic 4
  • naked mole-rat(101726411) cholinergic receptor, muscarinic 4

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
P6503
Pilocarpine hydrochloride, ≥99% (titration), powder,
Especie
human
A2251
Acetyl-β-methylcholine chloride, ≥98% (TLC), powder,
Especie
human
P6628
Pilocarpine nitrate salt, ≥98% (HPLC),
Especie
human
O100
Oxotremorine M, solid,
Especie
human
M104
(±)-Muscarine chloride hydrate, ≥98% (HPLC),
Especie
human

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
B1390
Bisacodyl, analytical standard, for drug analysis,
Especie
human
T9778
Tropicamide, solid,
Especie
human
A0257
Atropine sulfate salt monohydrate, ≥97% (TLC), crystalline,
Especie
human
S7882
(−)-Scopolamine N-butyl bromide, ≥98% (TLC), powder,
Especie
human
S8502
(−)-Scopolamine methyl bromide, ≥98% (HPLC), powder,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
MAB1578
Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 18C7.2, clone 18C7.2, Chemicon®, from mouse,
Reactividad de especies
monkey
Aplicación
immunohistochemistry
immunoprecipitation (IP)
western blot
ZMS1165
Anti-CHRM4 Antibody, clone 18C7.2 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
ELISA
affinity binding assay
immunocytochemistry
western blot
MAB1576
Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 17F10.2, purified antibody, clone 17F10.2, Chemicon®,
Reactividad de especies
monkey, mouse, rat
Aplicación
immunocytochemistry
immunoprecipitation (IP)
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
51330
Harmaline, ≥95%,
Especie
human, rat

Small Molecule - Ligand

Referencia del producto
Descripción
Especie
A138
Aminobenztropine, solid,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EMU046221
MISSION® esiRNA, targeting mouse Chrm4,
Especie
mouse