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Merck

CHAT

choline O-acetyltransferase

Sinónimos:
CHOACTASE, CMS1A, CMS1A2
Especie:
ID UniProtKB:
ID del gen:
  • Human(1103) Summary: This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010]
  • Mouse(12647) choline acetyltransferase
  • Rat(290567) choline O-acetyltransferase
  • Zebrafish(100170938) choline acetyltransferase
  • cow(524732) choline O-acetyltransferase
  • domestic cat(751512) choline O-acetyltransferase
  • dog(486775) choline O-acetyltransferase
  • chicken(395314) choline O-acetyltransferase
  • Thale Cress(821249) acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase
  • naked mole-rat(101711939) choline O-acetyltransferase
  • domestic guinea pig(100718930) choline O-acetyltransferase
  • sheep(101117817) choline O-acetyltransferase

Custom & Knockdown Gene Products

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Choline Acetyltransferase (ChAT) Antibody, clone 2K16, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-Choline Acetyltransferase Antibody, Chemicon®, from chicken,
Reactividad de especies
mouse
Aplicación
immunocytochemistry
immunohistochemistry
Anti-CHAT antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-Choline Acetyltransferase Antibody, Chemicon®, from rabbit,
Reactividad de especies
rat
Aplicación
ELISA
immunohistochemistry
Anticuerpo anti-colina acetiltransferasa, serum, Chemicon®,
Reactividad de especies
guinea pig, mouse, rat
Aplicación
immunohistochemistry
western blot

Small Molecule - Cofactor

Referencia del producto
Descripción
Especie
Acetil coenzimaA trisodium salt, ≥93% (HPLC), powder,
Especie
human, mouse, rat
Acetyl coenzyme A lithium salt, ≥93% (HPLC),
Especie
human, mouse, rat

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human CHAT,
Especie
human
MISSION® esiRNA, targeting mouse Chat,
Especie
mouse