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Merck

CENPJ

centromere protein J

Sinónimos:
BM032, CENP-J, CPAP, LAP, LIP1, MCPH6, SASS4, SCKL4, Sas-4
Especie:
ID UniProtKB:
ID del gen:
  • Human(55835) Summary: This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]
  • Mouse(219103) centromere protein J
  • Rat(305909) centromere protein J
  • Zebrafish(568957) centromere protein J
  • chicken(418960) centromere protein J
  • dog(486055) centromere protein J
  • domestic cat(101081107) centromere protein J
  • Horse(100049819) centromere protein J
  • cow(613543) centromere protein J
  • sheep(101119996) centromere protein J
  • domestic guinea pig(100712775) centromere protein J
  • naked mole-rat(101715831) centromere protein J

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Cenpj Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human CENPJ,
Especie
human
MISSION® esiRNA, targeting mouse Cenpj,
Especie
mouse