CCR5
chemokine (C-C motif) receptor 5 (gene/pseudogene)
Sinónimos:
CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22
Especie:
Human CCR5 (1234), Mouse Ccr5 (12774), Rat Ccr5 (117029), chicken CCR5 (420695), dog CCR5 (484789), domestic cat CCR5 (493769), cow CCR5 (497017), Horse CCR5 (100048935), sheep CCR5 (101117453), Domestic Rabbit CCR5 (100101579) ...Más
ID UniProtKB:
ID del gen:
- Human(1234) Summary: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(12774) chemokine (C-C motif) receptor 5
- Rat(117029) chemokine (C-C motif) receptor 5
- chicken(420695) chemokine (C-C motif) receptor 5
- dog(484789) chemokine (C-C motif) receptor 5
- domestic cat(493769) chemokine (C-C motif) receptor 5
- cow(497017) chemokine (C-C motif) receptor 5
- Horse(100048935) chemokine (C-C motif) receptor 5
- sheep(101117453) chemokine (C-C motif) receptor 5
- Domestic Rabbit(100101579) chemokine (C-C motif) receptor 5
- naked mole-rat(101723738) chemokine (C-C motif) receptor 5
- domestic guinea pig(100716672) chemokine (C-C motif) receptor 5
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Small Molecule - Antagonist
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Especie
Antibodies
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Descripción
Reactividad de especies
Aplicación
Anti-CCR5 (CD195) Antibody, clone HEK/1/85a/7a, clone HEK/1/85a/7a, from rat,
Reactividad de especies
human
Aplicación
flow cytometry
immunocytochemistry
immunocytochemistry
Anti-C-C Chemokine Receptor 5 Antibody, NT, Chemicon®, from rabbit,
Reactividad de especies
human
Aplicación
western blot
Anti-CCR5 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
Aplicación
immunohistochemistry
western blot
western blot