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Merck

CASP14

caspase 14, apoptosis-related cysteine peptidase

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(23581) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. [provided by RefSeq, Jul 2008]
  • Mouse(12365) caspase 14
  • Rat(299587) caspase 14
  • naked mole-rat(101720095) caspase 14, apoptosis-related cysteine peptidase
  • domestic guinea pig(100715745) caspase 14, apoptosis-related cysteine peptidase
  • sheep(101120827) caspase 14, apoptosis-related cysteine peptidase
  • chicken(776274) caspase 14, apoptosis-related cysteine peptidase
  • cow(517658) caspase 14, apoptosis-related cysteine peptidase
  • domestic cat(101099027) caspase 14, apoptosis-related cysteine peptidase
  • dog(610460) caspase 14, apoptosis-related cysteine peptidase

Custom & Knockdown Gene Products

  • siRNA

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Caspase-14 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-Caspase-14 Antibody, clone 6E2C1, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human CASP14,
Especie
human
MISSION® esiRNA, targeting mouse Casp14,
Especie
mouse