CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit
Sinónimos:
CACH2, CACN2, CACNL1A1, CCHL1A1, CaV1.2, LQT8, TS
Especie:
Human CACNA1C (775), Mouse Cacna1c (12288), Rat Cacna1c (24239), Zebrafish cacna1c (170581), cow CACNA1C (408015), Horse CACNA1C (100049924), chicken CACNA1C (395891), domestic cat CACNA1C (101082923), dog CACNA1C (403516), naked mole-rat Cacna1c (101717129) ...Más
ID UniProtKB:
ID del gen:
- Human(775) Summary: This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012]
- Mouse(12288) calcium channel, voltage-dependent, L type, alpha 1C subunit
- Rat(24239) calcium channel, voltage-dependent, L type, alpha 1C subunit
- Zebrafish(170581) calcium channel, voltage-dependent, L type, alpha 1C subunit
- cow(408015) calcium channel, voltage-dependent, L type, alpha 1C subunit
- Horse(100049924) calcium channel, voltage-dependent, L type, alpha 1C subunit
- chicken(395891) calcium channel, voltage-dependent, L type, alpha 1C subunit
- domestic cat(101082923) calcium channel, voltage-dependent, L type, alpha 1C subunit
- dog(403516) calcium channel, voltage-dependent, L type, alpha 1C subunit
- naked mole-rat(101717129) calcium channel, voltage-dependent, L type, alpha 1C subunit
- domestic guinea pig(100135490) calcium channel, voltage-dependent, L type, alpha 1C subunit
- Goat(100861292) calcium channel, voltage-dependent, L type, alpha 1C subunit
- sheep(101116562) calcium channel, voltage-dependent, L type, alpha 1C subunit
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