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Merck

BIRC7

baculoviral IAP repeat containing 7

Sinónimos:
KIAP, LIVIN, ML-IAP, MLIAP, RNF50
Especie:
ID UniProtKB:
ID del gen:
  • Human(79444) Summary: The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq, Jul 2008]
  • Mouse(329581) baculoviral IAP repeat-containing 7 (livin)
  • Rat(296468) baculoviral IAP repeat-containing 7
  • Zebrafish(100073331) baculoviral IAP repeat-containing 7
  • cow(514508) baculoviral IAP repeat containing 7
  • domestic cat(101080371) baculoviral IAP repeat containing 7
  • dog(485969) baculoviral IAP repeat containing 7
  • chicken(419239) baculoviral IAP repeat containing 7
  • sheep(101110435) baculoviral IAP repeat containing 7
  • domestic guinea pig(100717708) baculoviral IAP repeat containing 7
  • naked mole-rat(101709798) baculoviral IAP repeat containing 7

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Birc7/LIVIN Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, rhesus macaque
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human BIRC7,
Especie
human
MISSION® esiRNA, targeting mouse Birc7,
Especie
mouse