ACVR2A
activin A receptor, type IIA
Sinónimos:
ACTRII, ACVR2
Especie:
Human ACVR2A (92), Mouse Acvr2a (11480), Rat Acvr2a (29263), chicken ACVR2A (396324), dog ACVR2A (476140), domestic cat ACVR2A (101097750), Horse ACVR2A (100049823), cow ACVR2A (281598), sheep ACVR2A (443304), domestic guinea pig Acvr2a (100731791)
ID UniProtKB:
ID del gen:
- Human(92) Summary: This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013]
- Mouse(11480) activin receptor IIA
- Rat(29263) activin A receptor, type IIA
- chicken(396324) activin A receptor, type IIA
- dog(476140) activin A receptor, type IIA
- domestic cat(101097750) activin A receptor, type IIA
- Horse(100049823) activin A receptor, type IIA
- cow(281598) activin A receptor, type IIA
- sheep(443304) activin A receptor, type IIA
- domestic guinea pig(100731791) activin A receptor, type IIA
- naked mole-rat(101707586) activin A receptor, type IIA
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