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Merck

ACE

angiotensin I converting enzyme

Sinónimos:
ACE1, CD143, DCP, DCP1, ICH, MVCD3
Especie:
Human ACE (1636), Mouse Ace (11421), Rat Ace (24310), Zebrafish ace (565980), cow ACE (509484), Horse ACE (100064801), dog ACE (610668), chicken ACE (419953), fruit fly Ace (41625), sheep ACE (554335)
ID UniProtKB:
P12821, B0LPF0, B4DXI3, E7EU16, P22966, Q53YX9, Q59GY8, Q7M4L4
ID del gen:
  • Human(1636) Summary: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010]
  • Mouse(11421) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • Rat(24310) angiotensin I converting enzyme
  • Zebrafish(565980) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • cow(509484) angiotensin I converting enzyme
  • Horse(100064801) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • dog(610668) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • chicken(419953) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • fruit fly(41625) Acetylcholine esterase
  • sheep(554335) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
  • Domestic Rabbit(100009274) angiotensin I converting enzyme (peptidyl-dipeptidase A) 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
ZRB2821
Anti-ACE Antibody, clone 1E15 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, monkey, rat
Aplicación
affinity binding assay
immunofluorescence
immunohistochemistry
western blot
MAB3502-I
Anti-Angiotensin Converting Enzyme Antibody, clone 2E2, culture supernatant, clone 2E2, from mouse,
Reactividad de especies
human, rat
Aplicación
western blot
SAB5700960
Anti-ACE1 antibody produced in rabbit, ,
Reactividad de especies
mouse, rat
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
674974
6-Mercaptohexanoic acid, 90%,
Especie
rat
R0404
Ramipril, ≥98% (HPLC),
Especie
human
L6292
Lisinopril, ≥98% (HPLC),
Especie
human
PHR1446
Ramipril, Pharmaceutical Secondary Standard; Certified Reference Material,
Especie
human
1368609
Lisinopril, United States Pharmacopeia (USP) Reference Standard,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
A2580
Angiotensin Converting Enzyme from porcine kidney, lyophilized powder, ≥10 units/mg protein (Bradford),
Especie

esiRNA

Referencia del producto
Descripción
Especie
EHU160811
MISSION® esiRNA, targeting human ACE, CTD-2501B8.1,
Especie
human

Small Molecule - Substrate

Referencia del producto
Descripción
Especie
H1635
N-Hippuryl-His-Leu hydrate, powder, ≥98% (HPLC),
Especie
mouse, human, rat
F7131
N-[3-(2-furil)acriloil]-Phe-Gly-Gly, ,
Especie
mouse, human, rat
H4884
Hippuryl-His-Leu acetate salt, ,
Especie
mouse, human, rat