ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
Sinónimos:
ABC42, ALD, ALDP, AMN
Especie:
Human ABCD1 (215), Mouse Abcd1 (11666), Rat Abcd1 (363516), Zebrafish abcd1 (566367), dog ABCD1 (612520), cow ABCD1 (515178), domestic cat ABCD1 (101088223), sheep ABCD1 (101122673), Domestic Rabbit ABCD1 (100328741), naked mole-rat Abcd1 (101720585)
ID UniProtKB:
ID del gen:
- Human(215) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq, Jul 2008]
- Mouse(11666) ATP-binding cassette, sub-family D (ALD), member 1
- Rat(363516) ATP-binding cassette, subfamily D (ALD), member 1
- Zebrafish(566367) ATP-binding cassette, sub-family D (ALD), member 1
- dog(612520) ATP-binding cassette, sub-family D (ALD), member 1
- cow(515178) ATP-binding cassette, sub-family D (ALD), member 1
- domestic cat(101088223) ATP-binding cassette, sub-family D (ALD), member 1
- sheep(101122673) ATP-binding cassette, sub-family D (ALD), member 1
- Domestic Rabbit(100328741) ATP-binding cassette, sub-family D (ALD), member 1
- naked mole-rat(101720585) ATP-binding cassette, sub-family D (ALD), member 1
- domestic guinea pig(100713152) ATP-binding cassette, sub-family D (ALD), member 1
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Adrenoleukodystrophy Protein Antibody, a.a. 279-482, clone 2AL-1D6, ascites fluid, clone 2AL-1D6, Chemicon®,
Reactividad de especies
human
Aplicación
ELISA
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot