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Merck

ABCC11

ATP-binding cassette, sub-family C (CFTR/MRP), member 11

Sinónimos:
EWWD, MRP8, WW
Especie:
ID UniProtKB:
ID del gen:
  • Human(85320) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
  • sheep(101115563) ATP-binding cassette, sub-family C (CFTR/MRP), member 11
  • Domestic Rabbit(100359175) ATP-binding cassette, sub-family C (CFTR/MRP), member 11
  • dog(478138) ATP-binding cassette, sub-family C (CFTR/MRP), member 11
  • cow(100299784) ATP-binding cassette, sub-family C (CFTR/MRP), member 11
  • cow(101909197) ATP-binding cassette, sub-family C (CFTR/MRP), member 11
  • cow(522437) ATP-binding cassette sub-family C member 11-like
  • domestic cat(101089664) ATP-binding cassette, sub-family C (CFTR/MRP), member 11

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-MRP8 Antibody/ABCC11, clone 2, clone 2, from mouse,
Reactividad de especies
human
Aplicación
western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human ABCC11,
Especie
human