S3386
Sorbitan sesquioleate
nonionic surfactant
Synonym(s):
Arlacel® 83, Span® 83
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About This Item
CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:
NACRES:
NA.25
Recommended Products
biological source
corn
Quality Level
vapor pressure
0.81 psi ( 20 °C)
form
liquid
refractive index
n20/D 1.478 (lit.)
density
0.989 g/mL at 25 °C (lit.)
functional group
ester
lipid type
oils
shipped in
ambient
storage temp.
room temp
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General description
Sorbitan sesquioleate (SSO) is a sorbitol derivative emulsifier. It is a common emulsifier component in topical corticosteroids, topical antibiotics, topical antifungals, moisturizing creams and lotions and topical retinoids.
Biochem/physiol Actions
Sorbitan sesquioleate is useful as a stabilizing agent in polymerization process to produce spherical acrylamide beads. It has been used in many topical agents. SSO have recently been implicated in allergic dermatitis.
Other Notes
Fatty acid composition: Oleic acid (C18:1) approx. 70%; balance primarily palmitic acid (C16:0), stearic acid (C18:0) and linoleic acid (C18:2).
Legal Information
Arlacel is a registered trademark of Croda International PLC
Span is a registered trademark of Croda International PLC
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
235.4 °F - closed cup
Flash Point(C)
113 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Contact dermatitis.
Flora B de Waard-van der Spek et al.
Contact dermatitis, 59(1), 67-67 (2008-07-05)
E Larmi et al.
Contact dermatitis, 19(5), 368-371 (1988-11-01)
In order to study the effects of an emulsifier on non-immunologic immediate contact reactions, 500, 250, 125, 62, and 31 mM benzoic acid (BA) was tested in 12 medical students on a skin area of the upper back treated with
M Iwata et al.
Journal of microencapsulation, 16(1), 49-58 (1999-02-11)
PLGA multiphase microspheres were prepared by the multiple emulsion solvent evaporation method using acetonitrile as the polymer solvent and mineral oil as the evaporation medium. The preparation process was further developed in the present study to reduce the particle size
Kinetic evaluation of biotransformation of benzaldehyde to L-phenylacetylcarbinol by immobilized pyruvate decarboxylase from Candida utilis
Shin HS and Rogers PL
Biotechnology and Bioengineering, 49(4), 429-436 (1996)
Adam Asarch et al.
Dermatitis : contact, atopic, occupational, drug, 19(6), 339-341 (2009-01-13)
Sorbitol-based emulsifiers such as sorbitan sesquioleate (SSO) are commonly used in topical corticosteroids, topical antibiotics, topical antifungals, moisturizing creams and lotions, and topical retinoids. Contact dermatitis from sorbitol derivatives appears to be increasingly prevalent. Patch-testing with SSO can be useful
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