ZYX
zyxin
Synonyms:
ESP-2, HED-2
Species:
Human ZYX (7791), Mouse Zyx (22793), Rat Zyx (114636), fruit fly Zyx (317824), dog ZYX (482736), domestic cat ZYX (101099953), Zebrafish zyx (564246), chicken ZYX (418300), cow ZYX (768226), sheep ZYX (101123626) ...More
UniProtKB ID:
Gene ID:
- Human(7791) Summary: Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008]
- Mouse(22793) zyxin
- Rat(114636) zyxin
- fruit fly(317824) Zyxin
- dog(482736) zyxin
- domestic cat(101099953) zyxin
- Zebrafish(564246) zyxin
- chicken(418300) zyxin
- cow(768226) zyxin
- sheep(101123626) zyxin
- domestic guinea pig(100727523) zyxin
- naked mole-rat(101710025) zyxin
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Zyxin, serum, from rabbit,
Species Reactivity
human, monkey, mouse
Application
immunocytochemistry
western blot
western blot
Anti-Zyxin Antibody, clone 14E11.1, clone 14E11.1, from mouse,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
western blot
western blot
Anti-Zyxin Antibody, clone 4F9P3, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
immunofluorescence
western blot
western blot
Anti-Zyxin Antibody, clone 2F17 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey, mouse
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
esiRNA
Product Number
Description
Species