WDR35
WD repeat domain 35
Synonyms:
CED2, IFT121
Species:
Human WDR35 (57539), Mouse Wdr35 (74682), Rat Wdr35 (298876), Zebrafish wdr35 (565515), chicken WDR35 (421958), dog WDR35 (475677), domestic guinea pig Wdr35 (100723470), naked mole-rat Wdr35 (101721184), cow WDR35 (100337107), sheep WDR35 (101103137)
UniProtKB ID:
Gene ID:
- Human(57539) Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Two patients with Sensenbrenner syndrome / cranioectodermal dysplasia (CED) were identified with mutations in this gene, consistent with a possible ciliary function.[provided by RefSeq, Sep 2010]
- Mouse(74682) WD repeat domain 35
- Rat(298876) WD repeat domain 35
- Zebrafish(565515) WD repeat domain 35
- chicken(421958) WD repeat domain 35
- dog(475677) WD repeat domain 35
- domestic guinea pig(100723470) WD repeat domain 35
- naked mole-rat(101721184) WD repeat domain 35
- cow(100337107) WD repeat domain 35
- sheep(101103137) WD repeat domain 35
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